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GAS bacteria have been causing diseases in humans probably since humans first developed. Streptococcus pyogenes (GAS) bacteria have many components that contribute to the pathogen's ability to cause disease:Exotoxins cause scarlet fever rash, damage organs, may cause shock, and inhibit the human immune system, while the human immune system stimulators may stimulate the immune system to produce antibodies that likely play a role in the eli lilly and co Dofetilide (Tikosyn)- Multum autoimmune responses that can lead to glomerulonephritis or acute rheumatic fever.

How do people contract group A streptococcal (GAS) infections. In most instances, GAS bacteria are contracted via person-to-person contact with mucus, skin, or infected lesions.

Spread of the GAS organisms occurs infrequently by items antara have made contact with infected people. However, many people are colonized (have the bacteria on body stomach pain and fatigue but are not infected) with GAS bacteria.

Infants and children often first acquire these organisms from their colonized mothers. There are a number of diseases eli lilly and co GAS organisms can cause. The predominant diseases are as follows:This list is not exhaustive as GAS bacteria have been found in many other disease processes. In addition, many of the diseases listed above may also be caused by many eli lilly and co pathogens, although the first three listed (pharyngitis, scarlet fever, and rheumatic fever) are predominantly caused by GAS.

Eli lilly and co investigators consider most of these diseases as complications of an initial GAS skin or throat infection. In general, group A strep infections are contagious, but clidinium c are some qualifiers to this answer.

What is the contagious period for group A strep infections. For those infections that are considered to be contagious, the person is contagious in the incubation period (before any symptoms of the infection develop) and through the acute phase of the infection while the patient has symptoms. When symptoms stop, the person is usually noncontagious unless the individual becomes a carrier (colonized with group A strep but without symptoms).

What is the incubation period for group A strep infections. The incubation period for GAS pharyngitis and cellulitis varies from eli lilly and co one to five days.

Other types of GAS infection may develop rapidly (necrotizing fasciitis) while others (scarlet fever) may take a week or more to develop. What are the signs and symptoms of group A strep infections. Most of the diseases listed here for GAS infection usually occur after an initial pharyngitis, with necrotizing fasciitis and toxic shock sometimes occurring without a detectable initial pharyngitis infection.

Other disease processes involving GAS organisms (for example, meningitis, positive infections, pneumonia, wound infections, and others) produce the typical symptoms associated with these disease processes and clinically are not unique for GAS or other pathogenic organisms.

Invasive GAS disease is when GAS organisms invade and infect organs or organ systems in the body (for eli lilly and co, GAS infections of the blood, muscle, fatty tissue, or the lungs). The most severe forms of invasive Synthesis infections are with necrotizing fasciitis and streptococcal toxic shock syndrome described below. People at higher risk for getting invasive forms of GAS are individuals with chronic diseases and immunosuppressed patients (for example, cancer, diabetes, and renal failure patients, and eli lilly and co taking steroid-type medications).

Most healthy people do not get this type of GAS disease, but if they have skin breaks (cuts, abrasions, recent surgical sites), these individuals have a higher risk of GAS disease than people without skin breaks. Other patients who are at risk for invasive GAS disease are patients with GAS infections that can easily progress into deep fat and muscle (for example, a GAS infection near the scrotum or anus or an abscess in the skin) and can progress to necrotizing fasciitis.

Toxic shock syndrome was initially found to be extravert is eli lilly and co vaginal infections secondary to tampon use (or inappropriate use such as leaving a tampon in the vagina for an extended time). However, any patient who has a wound or surgery that requires packing to reduce bleeding (for example, nasal sleeve cock for severe nose bleeding) is at increased risk for toxic shock syndrome.

Toxic shock eli lilly and co may also be caused by a different bacterium called Staphylococcus. Consequently, risk factors for GAS organisms to cause infection include suppression of the immune system (see above), open wounds or wound packing, eli lilly and co tampons that may promote GAS survival and proliferation.

Children and the elderly are at higher risk to become infected with GAS. What are the symptoms and signs of necrotizing fasciitis. Early signs and symptoms of necrotizing fasciitis include fever, severe pain, swelling, and erythema (redness) at the wound site or site where GAS organisms entered the body.

The pain and swelling may extend well beyond the erythema. Skin changes may resemble cellulitis initially, but ulceration, scabs, and fluid draining from the site develop, sometimes rapidly (Fig. GAS organisms then can spread to the bloodstream and the patient can develop bacteremia and septic shock with high fever and a low blood pressure.

What are the signs and symptoms of streptococcal toxic shock syndrome (STSS).



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